Characteristics of some co-trimoxazole-resistant Enterobacteriaceae from infected patients.
نویسندگان
چکیده
Two isolates of Proteus mirabilis and four of Esch. coli which would not grow on commonly used commercial sensitivity test media are reported. These organisms appear to be resistant to co-trimoxazole, are exacting towards thymidine, and five of six were isolated from patients who had been treated with co-trimoxazole. A method for the detection of these strains is given and their significance in the laboratory and clinical practice discussed.
منابع مشابه
High Mortality from Blood Stream Infection in Addis Ababa, Ethiopia, Is Due to Antimicrobial Resistance
BACKGROUND Managing blood stream infection in Africa is hampered by lack of bacteriological support needed for antimicrobial stewardship, and background data needed for empirical treatment. A combined pro- and retrospective approach was used to overcome thresholds in clinical research in Africa. METHODS Outcome and characteristics including age, HIV infection, pancytopenia and bacteriological...
متن کاملردیابی ژن sul2 در اشریشیاکلی جداسازی شده از بیماران مبتلا به عفونتهای ادراری مراجعه کننده به مراکز کلینیکی شهر خوی
Background and Objective Widespread use of co-trimoxazole in urinary tract infection treatments and its incorrect use has led to the emergence of co-trimoxazole resistant E. coli strains. The aim of this study was to evaluate sul2 gene among E.coli isolates of patients admitted to the clinical centers of Khoy city. Materials and Methods: Three hundred urine samples were collected from clinic...
متن کاملFailure to demonstrate an advantage in combining sulphamethoxazole with trimethoprim in an experimental model of urinary infection.
Co-trimoxazole was found to have a predominantly bacteriostatic effect upon 28 urinary isolates of Enterobacteriaceae in nutrient broth and was never bactericidal in artificially infected urine. The components of co-trimoxazole were tested individually and trimethoprim was found to be at least as effective as co-trimoxazole in nutrient broth and in urine. Trimethoprim alone produced some bacter...
متن کاملDetermination of hemolysine genes frequency in antibiotic-resistant Staphylococcus aureus isolated from wound and urine samples of patients
Background: Staphylococcus aureus is a pathogenic bacterium that can target host cell membranes with virulence factors such as toxins and peptides. This study was evaluated the frequency of alpha, beta, and delta hemolysine genes in antibiotic-resistant Staphylococcus aureus isolated from patients' urine and wound samples. Materials and methods: This cross-sectional study was performed on 100 a...
متن کاملتوزیع فراوانی ژن های Sul1, Sul2, Sul3, drf7 درمقاومت به کوتریموکسازول در باسیلهای گرم منفی جدا شده از نمونه های بالینی بیماران بستری در بیمارستان پارس
Background and Aim: In the last few decades co-trimoxazole, an antibacterial combination of trimethoprim and sulfamethoxazole, has been used for treatment of bacterial infections, but due to the vast usage of these drugs, resistant strains have appeared throughout the world. One of the reasons for resistance to co-trimoxazole is related to drf genes, which are responsible for trimethoprim resis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of clinical pathology
دوره 25 12 شماره
صفحات -
تاریخ انتشار 1972